منابع مشابه
Metabolism of drugs. LXXX. The metabolic fate of nitrofuran derivatives. 3. Studies on enzymes in small intestinal mucosa of rat catalyzing degradation of nitrofuran derivatives.
The enzymes responsible for the degradation of nitrofuran derivatives in rat small intestinal mucosa were examined in vitro.As a result,it was suggested that the initial reactions in the degradation of 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide(AF-2) and 5-nitro-2-furfural semicarbazone(nitrofurazone)are mainly catalyzed by xanthine oxidase , while that of 2-amino-5-[2-(5-nitro-2-fury1)-1-(2-fur...
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The induction of unscheduled DNA synthesis in primary cultures of urothelial cells from rats, mice, and dogs by nitrofurans and arylamines and their derivatives was examined. Electron microscopy of the culture from rat cells showed the characteristics of epithelial cells. The cultured cells were exposed to the test chemicals in a serum-free medium containing 10 mM hydroxyurea and [3H]thymidine ...
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Some novel ester imides synthesised from trimellitic acid anhydride and 1-adamantanol or 2-adamantanol, were tested as antimicrobial compounds. Unfortunately, these agents showed a modest antibacterial activity (MIC > 6 microg/ml). However, a comparison of these N-substituted adamantylester imides with the series published previously, indicated that the incorporation of L-alanine and L-phenylal...
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A versatile automated synthesis apparatus, equipped with a chemical artificial intelligence, was developed to prepare and isolate a wide variety of compounds. The apparatus was to the synthesis of substituted N-(carboxyalkyl)amino-acids. The apparatus [1,2] is composed of units for performing various tasks,for example reagent supply, reaction, purification and separation, each linked to a contr...
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Iron (III) phosphate catalyzed condensation reaction of aldehydes, 1,3-dicarbonyl compounds and amuniom acetate refluxing ethanol that remains a common theme in current literature.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1965
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.85.8_744